Physics-based Super-Accuracy Molecular Dynamics Simulation Integrated With Artificial Intelligence Algorithms To Solve Biophysics Problems in Living Cells
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2023.4. Grant awarded: 과학기술정보통신부
앞으로 4년 동안 "Artificial intelligence for prediction of structure-based protein interaction reflecting physicochemical principles"에 참여하게 되었습니다.
연구에 참여할 대학원생 및 포스트닥은 연락주세요.
2023.3. Papers accepted: Nature Communications
Three papers in collaboration with expeimentalists at Korea University and KRIBB.
"Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore"
"Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM"
"Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel"
2022. Paper accepted: Soft Matter
"Aggregation or phase separation can be induced in highly charged proteins by small charged biomolecules"
2021.8. Paper accepted: Nucleic Acids Research
"DNA Sequence and Methylation Prescribe the Inside-Out Conformational Dynamics and Bending Energetics of DNA Minicircles"
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2021.03. Grant awarded: 과학기술정보통신부
앞으로 4년 동안 "인공지능(AI) 혁신 허브 사업"에 참여하게 되었습니다.
AI를 이용한 단백질 구조 연구를 수행합니다.
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2020.09. Grant awarded: 한국연구재단 NRF
한국연구재단 개인연구지원사업(중견연구)에 선정되어 5년 동안 연구비를 지원받습니다.
연구주제는 "초고정밀 분자 모델링을 이용한 DNA 결합 단백질의 확산기작 규명"입니다.
Paper accepted: Current Opinion in Structural Biology
“Molecular Dynamics Simulations of DNA-DNA and DNA-Protein Interactions”
Paper accepted: Journal of Chemical Theory and Computation
“Improved Parameterization of Protein−DNA Interactions for Molecular Dynamics Simulations of PCNA Diffusion on DNA”
Cool 1 µs/day folding simulations on desktop!
We're furnishing our lab with workstations powered by water-cooled RTX 2080 ti GPU cards. Water-cooled RTX 2080 ti (temperature below 50℃) is twice faster than air-cooled GTX 1080 ti (temperature over 80℃). See our benchmark page for details.
Earned huge supercomputer time from National Supercomputing Center!
7 Apr 2020: We received 274,000 node-hour Nurion supercomputer time from National Supercomputing Center.
Open positions in SKKU biophysics lab
As of Mar 2020, Jejoong started a new position as an assistant professor at SKKU physics. Please contact Jejoong at jejoong@skku.edu for open positions for postdocs & graduate/undergraduate research assistants.
15 Aug 2018: Our 20-node cluster is finally functional. Each node has 48-core AMD Epyc CPU and 2 Nvidia 1080Ti GPU cards.
We have open positions for postdocs & undergraduate research assistants. Please contact Jejoong at jejoong@ibs.re.kr.
15 Jul 2018: Our paper on “Sequence-dependent DNA condensation as a driving force of DNA phase separation” was published in Nucleic Acids Research.
15 Apr 2018: Dr. Stefan Ivanov joined our team!
28 Feb 2018: We published a perspective in PCCP summarizing our (and others) efforts to improve the force fields.
Dec 2017: Sujae Jung joined our team as an undergraduate research assistant during winter!
Nov 2017: Sunjoo You joined our team as an undergraduate research assistant!
1 Aug 2017: Jejoong Yoo started working in the Center for Self-assembly & Complexity (CSC) at Institute for Basic Science (IBS).